

It is the primary skin control cream for red skin care due to problematic skin or sebum excess.
The main ingredient, nicotinamide, improves the problematic skin condition.

Comparison of the efficacy of topical nicotinamide 4% vs topical clindamycin phosphate 1% gel in the treatment of inflammatory acne vulgaris. After 8 weeks of treatment, the topical nicotinamide is slightly superior to the clindamycin gel at reducing acne severity(A) and improving acne condition as assessed by the physician’s global evaluation (B)(n=38 per group; P not significant error not shown). Adapted with permission from shalita et al. Blackwell Publishing.

Papule

Pustule

Nodule
Acne Rosacea prevention Diminish acne vulgaris




Inhibits leukocytic chemotaxis

Inhibits lymphocytic transformation and antibody production

Lymphocyte

Transformed lymphocyte plasma cell

P. acnes antibodies
