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Hair Treatment

Hairlopecia – Transdermal Scalp Delivery Systems

By 2025-08-07No Comments

Hair loss is a multifactorial condition influenced by genetics, hormones, inflammation, oxidative stress, and lifestyle factors. While oral medications and topical applications have long been standard approaches, it can significantly limit ingredient absorption – especially in individuals with thickened stratum corneum or compromised microcirculation. Clinical insights suggest that an effective treatment depends on the successful delivery of active substances to the dermal layer, where hair follicles are located.

This brings us to transdermal delivery systems, which bypass the scalp’s surface barrier, ensuring that therapeutic actives reach their intended targets—without systemic side effects.

 

RIBESKIN Hairlopecia Meso Complex hair loss treatment

With this focus, RIBESKIN introduces the Hairlopecia range, a next-generation scalp care system comprising two advanced formulations:

RIBESKIN Hairlopecia Meso Complex hair loss treatment

Hairlopecia is suitable for patients with:

  • Early to moderate androgenetic alopecia
  • Hair thinning due to stress, hormonal imbalance, or inflammation
  • Postpartum hair loss
  • Scalp microinflammation, sensitivity, or dysseborrhea

These two treatments are designed for professional in-clinic protocols in combination with at-home self care protocols. They are formulated to meet the growing clinical need for precision, biocompatibility, and deep follicular impact.

 

Follicle Activating Complex

 

At the core of Hairlopecia Meso Complex lies a patented pea peptide complex. This botanical peptide has been shown to activate dermal papilla cells, which play a key role in the anagen (growth) phase of the hair cycle. The low molecular weight peptides of under 5,000 Daltons enhance the absorption in the scalp. Pea Peptide helps in preventing hair loss by reducing the activity of TGF-β, one of the signaling molecules related to hair loss in Dermal Papilla Cells (DPC), which are responsible for hair generation. Pea-Peptide’s effect on promoting hair growth and preventing hair loss has been proven through clinical trials, check out the detailed study here.

Apart from Pea Peptide, Hairlopecia Meso Complex is fortified with scalp essential nutrients like Biotin, PDRN, EGF, Coenzyme Q10, Amino acid complex and Panthenol. This combination offers a dual approach—addressing both regeneration and protection, critical in managing hair loss caused by both internal and external factors. 

 

Delivery System 1: Scalp Activator

Hairlopecia utilizes a scalp activator with multiple, uniform micro-channels, to maximize the absorption of active ingredients. This targeted delivery not only boosts the bioavailability of regenerative actives but also initiates microcirculation and cellular turnover – two key factors in promoting a healthier scalp environment. Its transdermal absorption with minimal pain & discomfort makes it a clinically advanced option for patients who require more than just surface-level stimulation.

 

 

Delivery System 2: Micro Silica

Expanding on the original formulation, Hairlopecia Meso Complex & Micro Silica integrates high-purity spicules. These biological micro-needle-like particles aid in exfoliating dead scalp keratin and help open micro-channels in the scalp, enhancing transdermal absorption of above active ingredients. The result is improved blood circulation, reduced scalp inflammation, and a primed scalp environment for better hair follicle nutrition and activation—making it ideal for patients with poor scalp cell turnover or resistant hair thinning cases.

 

RIBESKIN Hairlopecia Meso Complex hair loss treatment

 

Clinical Results

RIBESKIN Hairlopecia Meso Complex before and after treatment image
Results in a 50s aged male, after 8 Treatments for 8 Weeks. Combined treatment of weekly Hairlopecia Meso Complex (using Scalp Activator) along with daily self care with Hairlopecia Micro Silica

RIBESKIN Hairlopecia Meso Complex before and after treatment image
Results in a 30s aged female, after 8 Treatments for 8 Weeks. Combined treatment of weekly Hairlopecia Meso Complex (using Scalp Activator) along with daily self care with Hairlopecia Micro Silica

With dual transdermal delivery options, Hairlopecia offers a versatile, clinic-ready protocol designed to meet a wide range of patient needs. It’s a forward-thinking approach to hair loss management—grounded in science, backed by results.

 

 

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